Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.38 |
| ▸ | FURIN | P09958 | 3/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | GRB2 | P62993 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29077887 | 1.00 | PTPN1 (0.38) | PTPN1FURINMAP1LC3BKMT2APSMB5 | |
| SCHEMBL29077888 | 1.00 | PTPN1 (0.38) | PTPN1FURINMAP1LC3BKMT2APSMB5 | |
| SCHEMBL29077877 | 1.00 | PTPN1 (0.38) | PTPN1FURINMAP1LC3BKMT2APSMB5 | |
| SCHEMBL29077926 | 1.00 | PTPN1 (0.38) | PTPN1FURINMAP1LC3BKMT2APSMB5 | |
| SCHEMBL31041108 | 1.00 | PTPN1 (0.38) | PTPN1FURINMAP1LC3BKMT2APSMB5 | |
| SCHEMBL29610198 | 0.95 | PTPN1 (0.37) | PTPN1FURINMAP1LC3BPSMB5SSTR3 | |
| SCHEMBL29609019 | 0.95 | PTPN1 (0.37) | PTPN1FURINMAP1LC3BPSMB5SSTR3 | |
| SCHEMBL29609496 | 0.95 | PTPN1 (0.37) | PTPN1FURINMAP1LC3BPSMB5SSTR3 | |
| SCHEMBL23880537 | 0.95 | MAP1LC3B (0.37) | PTPN1FURINMAP1LC3BSIRT5SSTR3 | |
| SCHEMBL19432556 | 0.95 | MAP1LC3B (0.37) | PTPN1FURINMAP1LC3BSIRT5SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085100-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116390771-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2023-07-04 | — | — | CN | disclosed |