SCHEMBL29078271

SCHEMBL29078271

CCC#CCn1ncc(-c2ccc(C(F)(F)F)cc2)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
TLR8 Q9NR97 1/20 0.38
BIRC5 O15392 1/20 0.37
KCNH2 Q12809 1/20 0.37
EPHB4 P54760 2/20 0.37
TEK Q02763 2/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
NFKB1 P19838 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
HSD17B10 Q99714 1/20 0.35
F2RL3 Q96RI0 1/20 0.35
KIF11 P52732 2/20 0.35
PDE2A O00408 1/20 0.34
DYRK3 O43781 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29077838 0.85 KDM4E (0.36) CTSSCTSKKDM4EHPGDKIF11
SCHEMBL29077904 0.82 KCNH2 (0.40) KCNH2
SCHEMBL29821025 0.82 KCNH2 (0.40) KCNH2
SCHEMBL29077909 0.82 TNF (0.39)
SCHEMBL29821089 0.82 TNF (0.39)
SCHEMBL29078269 0.77 JAK2 (0.40) DYRK1ADYRK1BKDR
SCHEMBL29078210 0.77 CYP1A2 (0.35) CYP1A2
SCHEMBL29821800 0.77 CYP1A2 (0.35) CYP1A2
SCHEMBL29077854 0.75 EPHB4 (0.51) EPHB4TEKPTGS2KDR
SCHEMBL29077847 0.74 LMNA (0.56) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4284783-A1 AZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2023-12-06 EP claimed
CN-116745266-A Azole compounds for controlling invertebrate pests FMC公司 2023-09-12 CN claimed
WO-2022164857-A1 AZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION (US) 2022-08-04 WO claimed
EP-4284783-A1 AZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2023-12-06 EP disclosed
CN-116745266-A Azole compounds for controlling invertebrate pests FMC公司 2023-09-12 CN disclosed
WO-2022164857-A1 AZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION (US) 2022-08-04 WO disclosed