Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24297227 | 1.00 | CA2 (0.41) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL29077879 | 0.89 | FURIN (0.40) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL24297209 | 0.89 | FURIN (0.40) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL25787504 | 0.88 | FURIN (0.40) | SIRT5FURINMAP1LC3B | |
| SCHEMBL15699736 | 0.88 | FURIN (0.40) | SIRT5FURINMAP1LC3B | |
| SCHEMBL12283259 | 0.88 | CA2 (0.46) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL20158426 | 0.88 | CA2 (0.46) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL14012279 | 0.88 | CA2 (0.46) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL17902993 | 0.88 | CA2 (0.46) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL13436625 | 0.88 | CA2 (0.46) | CA2CA1MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085100-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116390771-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2023-07-04 | — | — | CN | disclosed |