Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916491 | 0.88 | CRBN (0.42) | CRBNCYP3A4HPGD | |
| SCHEMBL2913186 | 0.87 | CRBN (0.41) | CRBNCYP3A4 | |
| SCHEMBL2915298 | 0.84 | CRBN (0.56) | CRBNCYP3A4HPGD | |
| SCHEMBL2912422 | 0.82 | CRBN (0.40) | CRBNCYP3A4 | |
| SCHEMBL1530921 | 0.82 | CRBN (0.64) | CRBNCYP3A4HPGD | |
| SCHEMBL1530923 | 0.82 | CRBN (0.64) | CRBNCYP3A4HPGD | |
| SCHEMBL2910151 | 0.82 | CRBN (0.43) | CRBNCYP3A4 | |
| SCHEMBL3773011 | 0.79 | CRBN (0.42) | CRBNCYP3A4 | |
| SCHEMBL2915236 | 0.79 | CRBN (0.46) | CRBNCYP3A4 | |
| SCHEMBL1530126 | 0.79 | CRBN (0.40) | CRBNCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |