Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.30 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915298 | 0.87 | CRBN (0.56) | CRBNCYP3A4 | |
| Methyl Alcohol SCHEMBL2913736 | 0.82 | CRBN (0.67) | CRBNCYP3A4 | |
| SCHEMBL1530876 | 0.82 | CRBN (0.69) | CRBNCYP3A4FPR1FPR2EGFR | |
| SCHEMBL2913931 | 0.82 | CRBN (0.69) | CRBNCYP3A4 | |
| Alcohol SCHEMBL2909873 | 0.82 | CRBN (0.64) | CRBNCYP3A4 | |
| Water SCHEMBL2915433 | 0.81 | CRBN (0.68) | CRBNCYP3A4 | |
| SCHEMBL2913574 | 0.81 | RARB (0.39) | CRBN | |
| Propanol SCHEMBL2911013 | 0.80 | CRBN (0.62) | CRBNCYP3A4 | |
| Isopropyl Alcohol SCHEMBL2910113 | 0.80 | CRBN (0.64) | CRBNCYP3A4 | |
| SCHEMBL2910151 | 0.80 | CRBN (0.43) | CRBNCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |