Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 9/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914545 | 0.83 | CYP1A2 (0.40) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL3001859 | 0.81 | CYP1A2 (0.39) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL3001864 | 0.81 | CYP1A2 (0.39) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL6053569 | 0.78 | CYP1A2 (0.40) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL2908881 | 0.78 | CYP1A2 (0.40) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL2983884 | 0.78 | CYP1A2 (0.37) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL2983874 | 0.78 | CYP1A2 (0.37) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL2906181 | 0.76 | ABCB11 (0.40) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL2913683 | 0.76 | SLC29A1 (0.37) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 | |
| SCHEMBL4271729 | 0.76 | CYP1A2 (0.35) | CYP1A2ADORA2AADORA1SLC29A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |
| EP-1358198-A4 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2008-03-05 | — | — | EP | claimed |
| EP-1358198-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG Chem Investment, Ltd. (KR) | 2003-11-05 | — | — | EP | claimed |
| WO-2002057288-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD. (KR) | 2002-07-25 | — | — | WO | claimed |