Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12080834 | 0.79 | POLB (0.61) | ALDH1A1MAPTPOLBTP53LMNA | |
| SCHEMBL29079095 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBTP53LMNA | |
| SCHEMBL4767957 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL5004868 | 0.72 | ACACB (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21928103 | 0.70 | POLB (0.57) | ALDH1A1POLBLMNAKMT2A | |
| SCHEMBL29079094 | 0.70 | GRIA2 (0.44) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL10587273 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBTP53KDM4E | |
| SCHEMBL15507004 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTPOLBKDM4EHPGD | |
| SCHEMBL3665175 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL12957768 | 0.65 | ALDH1A1 (0.47) | ALDH1A1MAPTTP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640094-A | Compounds as PRMT1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |