Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574134 | 0.86 | OPRL1 (0.47) | TNKSOPRL1OPRM1OPRK1 | |
| SCHEMBL30447595 | 0.81 | TNKS (0.42) | MEN1KMT2ATNKSOPRL1OPRM1 | |
| SCHEMBL30448104 | 0.81 | TNKS (0.42) | MEN1KMT2ATNKSOPRL1OPRM1 | |
| SCHEMBL10063517 | 0.78 | OPRL1 (0.41) | TNKSOPRL1OPRM1OPRK1 | |
| SCHEMBL30898629 | 0.76 | MEN1 (0.46) | MEN1CYP2C9KMT2ATNKSOPRL1 | |
| SCHEMBL20066137 | 0.76 | OPRM1 (0.54) | MEN1CYP2C9KMT2AOPRL1OPRM1 | |
| SCHEMBL24204284 | 0.75 | OPRL1 (0.65) | OPRL1OPRM1OPRK1 | |
| SCHEMBL28050723 | 0.74 | TNKS (0.53) | MEN1CYP2C9KMT2ATNKSNOTUM | |
| SCHEMBL30666913 | 0.73 | CNR1 (0.49) | MEN1CYP2C9KMT2AOPRL1OPRM1 | |
| SCHEMBL25036306 | 0.72 | CRBN (0.56) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640094-A | Compounds as PRMT1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |