SCHEMBL29079129 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	AAK1	Q2M2I8	10/20	0.50

▸	PPARA	Q07869	4/20	0.45

▸	PPARG	P37231	3/20	0.45

▸	CTSS	P25774	2/20	0.42

▸	CTSK	P43235	2/20	0.42

▸	CTSB	P07858	1/20	0.42

▸	ACE	P12821	1/20	0.41

▸	GSTP1	P09211	1/20	0.40

▸	GSTM2	P28161	1/20	0.40

▸	ALDH1A1	P00352	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30037723	1.00	AAK1 (0.50)	AAK1PPARAPPARGCTSSCTSK
SCHEMBL15964631	1.00	AAK1 (0.50)	AAK1PPARAPPARGCTSSCTSK
SCHEMBL20477379	0.92	AAK1 (0.48)	AAK1PPARAPPARGCTSSCTSK
SCHEMBL20477382	0.92	AAK1 (0.48)	AAK1PPARAPPARGCTSSCTSK
SCHEMBL8904021	0.88	ALDH1A1 (0.52)	PPARAPPARGALDH1A1
SCHEMBL17321186	0.88	ALDH1A1 (0.52)	PPARAPPARGALDH1A1
SCHEMBL27373894	0.88	ALDH1A1 (0.52)	PPARAPPARGALDH1A1
SCHEMBL1561539	0.88	MAPT (0.47)	AAK1PPARAPPARGACEGSTP1
SCHEMBL1561542	0.88	MAPT (0.47)	AAK1PPARAPPARGACEGSTP1
SCHEMBL8903728	0.88	PPARA (0.45)	AAK1PPARAPPARGCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116640156-A	RIPK1 inhibitors	上海齐鲁制药研究中心有限公司	2023-08-25	—	—	CN	disclosed