Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.60 |
| ▸ | GLA | P06280 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | CASP1 | P29466 | 4/20 | 0.50 |
| ▸ | CASP7 | P55210 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477917 | 0.95 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL30483544 | 0.95 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL26970375 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL9442782 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL28854634 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL30502405 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL28854650 | 0.83 | GAA (0.66) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL30502408 | 0.83 | GAA (0.66) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL28854641 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL29079165 | 0.80 | KDM4E (0.54) | ALDH1A1KDM4EGAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601145-A | Potent and selective calcium-activated potassium channel K for plateau treatment Ca 3.1 inhibitors | 南洋理工大学 | 2023-08-15 | — | — | CN | disclosed |