SCHEMBL29079334

SCHEMBL29079334

CC(C)(Oc1ccc(CCNc2ccc(-c3ccccc3)cc2)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.62
PPARA Q07869 10/20 0.62
KDM4E B2RXH2 2/20 0.60
MAPT P10636 1/20 0.60
ADRB3 P13945 3/20 0.58
PPARD Q03181 3/20 0.53
ALDH1A1 P00352 2/20 0.53
FABP2 P12104 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2517277 0.92 PPARG (0.60) PPARGPPARAKDM4EMAPTADRB3
SCHEMBL29079323 0.85 ADRB3 (0.56) PPARGPPARAKDM4EMAPTADRB3
SCHEMBL12228621 0.84 PPARG (0.60) PPARGPPARAKDM4EMAPTADRB3
SCHEMBL11683879 0.81 PPARA (0.74) PPARGPPARAKDM4EMAPTADRB3
SCHEMBL3848024 0.81 ADRB3 (0.73) PPARGPPARAKDM4EMAPTADRB3
SCHEMBL9274728 0.81 PPARA (0.58) PPARGPPARAKDM4EMAPTADRB3
SCHEMBL9416379 0.81 PPARA (0.65) PPARGPPARAKDM4EMAPTPPARD
SCHEMBL14584458 0.81 PPARG (0.81) PPARGPPARAPPARD
SCHEMBL29079360 0.80 MEN1 (0.63) PPARGPPARAKDM4EMAPTALDH1A1
SCHEMBL5660957 0.80 PPARG (0.81) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116803977-A Preparation method and application of phenoxyacetic acid derivative 中国人民解放军军事科学院军事医学研究院 2023-09-26 CN claimed
CN-117417279-A Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2024-01-19 CN disclosed
CN-116803977-A Preparation method and application of phenoxyacetic acid derivative 中国人民解放军军事科学院军事医学研究院 2023-09-26 CN disclosed