Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.73 |
| ▸ | PPARA | Q07869 | 9/20 | 0.66 |
| ▸ | PPARG | P37231 | 13/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | FABP2 | P12104 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840876 | 0.95 | ADRB3 (0.67) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL12328025 | 0.95 | ADRB3 (0.67) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL12953097 | 0.90 | PPARG (0.71) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL2517277 | 0.86 | PPARG (0.60) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL3841460 | 0.85 | PPARA (0.59) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL3288292 | 0.85 | PPARA (0.57) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL1352258 | 0.85 | ADRB3 (1.00) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL1351960 | 0.85 | ADRB3 (1.00) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL1352261 | 0.85 | ADRB3 (1.00) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL11566625 | 0.83 | PPARG (0.70) | ADRB3PPARAPPARGMAPTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |