Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | BCHE | P06276 | 3/20 | 0.68 |
| ▸ | ACHE | P22303 | 3/20 | 0.68 |
| ▸ | RORC | P51449 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | WNT3A | P56704 | 1/20 | 0.61 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420808 | 0.90 | EPHX2 (0.79) | MEN1KMT2ABCHEACHEEPHX2 | |
| SCHEMBL3714852 | 0.90 | KMT2A (1.00) | MEN1KMT2ABCHEACHERORC | |
| SCHEMBL4420812 | 0.90 | EPHX2 (0.79) | MEN1KMT2ABCHEACHEEPHX2 | |
| SCHEMBL29167259 | 0.86 | KMT2A (0.69) | MEN1KMT2ABCHEACHEEPHX2 | |
| SCHEMBL1948079 | 0.85 | KMT2A (0.83) | MEN1KMT2ARORCEPHX2WNT3A | |
| SCHEMBL8331684 | 0.83 | MEN1 (0.79) | MEN1KMT2ARORCEPHX2WNT3A | |
| SCHEMBL1283623 | 0.83 | KMT2A (0.79) | MEN1KMT2ABCHEACHERORC | |
| SCHEMBL19827071 | 0.83 | MEN1 (0.73) | MEN1KMT2ARORCEPHX2WNT3A | |
| SCHEMBL10054999 | 0.82 | EPHX2 (0.92) | MEN1KMT2ABCHEACHEEPHX2 | |
| SCHEMBL5197660 | 0.82 | MEN1 (0.72) | MEN1KMT2ARORCEPHX2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417279-A | Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application | 中国人民解放军军事科学院军事医学研究院 | 2024-01-19 | — | — | CN | disclosed |
| CN-116803977-A | Preparation method and application of phenoxyacetic acid derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-09-26 | — | — | CN | disclosed |