SCHEMBL1948079

SCHEMBL1948079

O=C(Cc1ccc(-c2ccccc2)cc1)Nc1cc(NC(=O)Cc2ccc(-c3ccccc3)cc2)cc(NC(=O)Cc2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.83
MEN1 O00255 7/20 0.83
EPHX2 P34913 1/20 0.65
RORC P51449 1/20 0.62
WNT3A P56704 2/20 0.62
SLC6A2 P23975 1/20 0.60
SLC6A3 Q01959 1/20 0.60
ALDH1A1 P00352 4/20 0.60
LMNA P02545 3/20 0.60
NPC1 O15118 2/20 0.58
PKM P14618 1/20 0.58
ABCC4 O15439 1/20 0.58
GAA P10253 1/20 0.58
TSHR P16473 1/20 0.58
PTGS1 P23219 1/20 0.58
HTT P42858 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
CFD P00746 1/20 0.57
RAB9A P51151 2/20 0.57
HPGD P15428 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3714852 0.91 KMT2A (1.00) KMT2AMEN1EPHX2RORCWNT3A
SCHEMBL29079378 0.85 MEN1 (0.81) KMT2AMEN1EPHX2RORCWNT3A
SCHEMBL8331684 0.83 MEN1 (0.79) KMT2AMEN1EPHX2RORCWNT3A
SCHEMBL1283623 0.83 KMT2A (0.79) KMT2AMEN1EPHX2RORCWNT3A
SCHEMBL253845 0.83 KMT2A (0.72) KMT2AMEN1EPHX2RORCWNT3A
SCHEMBL4300884 0.83 KMT2A (0.72) KMT2AMEN1EPHX2RORCALDH1A1
SCHEMBL6098738 0.83 CFD (0.81) KMT2AMEN1EPHX2ALDH1A1LMNA
SCHEMBL10054999 0.83 EPHX2 (0.92) KMT2AMEN1EPHX2ALDH1A1NPC1
SCHEMBL11900270 0.81 EPHX2 (0.81) KMT2AMEN1EPHX2ALDH1A1LMNA
SCHEMBL29167259 0.81 KMT2A (0.69) KMT2AMEN1EPHX2ALDH1A1CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
EP-2510047-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2012-10-17 EP disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
WO-2011071718-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2011-06-16 WO disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed