Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537663 | 1.00 | GRM2 (0.50) | GRM2GAASMN1; SMN2CMA1DRD4 | |
| SCHEMBL16466966 | 0.77 | GAA (0.49) | GRM2GAASMN1; SMN2CMA1DRD4 | |
| SCHEMBL16589758 | 0.76 | F9 (0.47) | SMN1; SMN2KMT2A | |
| SCHEMBL16589755 | 0.76 | GRM2 (0.49) | GRM2DRD4SIGMAR1 | |
| SCHEMBL14935178 | 0.75 | GRM2 (0.46) | GRM2GAASMN1; SMN2DRD4MEN1 | |
| SCHEMBL2016909 | 0.75 | GAA (0.49) | GRM2GAACMA1GSK3AGSK3B | |
| SCHEMBL5638987 | 0.75 | GAA (0.49) | GRM2GAACMA1GSK3AGSK3B | |
| SCHEMBL3264320 | 0.75 | GAA (0.52) | GRM2GAACMA1GSK3AGSK3B | |
| SCHEMBL15922327 | 0.75 | TACR1 (0.51) | GRM2DRD4MEN1KMT2ASIGMAR1 | |
| SCHEMBL173296 | 0.74 | GAA (0.51) | GRM2GAASMN1; SMN2CMA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648248-B | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-116648248-A | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022161414-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND APPLICATION THEREOF | 成都茵创园医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |