Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915057 | 0.85 | CRBN (0.39) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL2907766 | 0.85 | KMT2A (0.41) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL1530810 | 0.84 | AURKB (0.39) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL2907824 | 0.84 | MAPT (0.39) | MAPTALDH1A1L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL2913875 | 0.83 | F10 (0.37) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL2910755 | 0.81 | MAPT (0.38) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL2915689 | 0.81 | F10 (0.39) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL2915054 | 0.81 | NR1H4 (0.40) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL2913600 | 0.81 | NR1H4 (0.40) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL2913384 | 0.81 | NR1H4 (0.40) | KMT2AMAPTMEN1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |