Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913875 | 0.94 | F10 (0.37) | F10CRBNMEN1KMT2ARAB9A | |
| SCHEMBL2915057 | 0.86 | CRBN (0.39) | F10CRBNMEN1KMT2ARAB9A | |
| SCHEMBL2907766 | 0.85 | KMT2A (0.41) | F10CRBNMEN1KMT2ARAB9A | |
| SCHEMBL1530859 | 0.83 | AURKB (0.43) | F10CRBNMEN1KMT2ARAB9A | |
| SCHEMBL2910755 | 0.83 | MAPT (0.38) | F10CRBNMEN1KMT2ARAB9A | |
| SCHEMBL2915255 | 0.83 | BRAF (0.37) | F10RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL2907824 | 0.83 | MAPT (0.39) | RAB9AKIF18AALDH1A1RXFP1NPC1 | |
| SCHEMBL2907962 | 0.81 | KMT2A (0.38) | CRBNMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2913384 | 0.81 | NR1H4 (0.40) | F10MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2913600 | 0.81 | NR1H4 (0.40) | F10MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |