Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626047 | 0.86 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL6910042 | 0.86 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL17636790 | 0.86 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL16824931 | 0.83 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2ENPP2 | |
| SCHEMBL18186257 | 0.83 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2ENPP2 | |
| SCHEMBL18186392 | 0.83 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2ENPP2 | |
| SCHEMBL38662270 | 0.83 | GPR119 (0.46) | MAPTALDH1A1LMNAGPR119LIPE | |
| SCHEMBL23887676 | 0.82 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL18186332 | 0.82 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL16824914 | 0.82 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406259-A | Dosage form compositions comprising inhibitors of BTK and mutants thereof | 广州麓鹏制药有限公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-4196124-A1 | DOSAGE FORM COMPOSITIONS COMPRISING AN INHIBITOR OF BTK AND MUTANTS THEREOF | Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022036171-A1 | DOSAGE FORM COMPOSITIONS COMPRISING AN INHIBITOR OF BTK AND MUTANTS THEREOF | NEWAVE PHARMACEUTICAL INC. (US) | 2022-02-17 | — | — | WO | disclosed |