SCHEMBL29079727

SCHEMBL29079727

CC(C)(C)OC(=O)N1CCC(Oc2cccc(Br)c2F)CC1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 11/20 0.55
KDM1A O60341 1/20 0.55
PDE4D Q08499 3/20 0.48
PDE4B Q07343 3/20 0.48
PDE4A P27815 2/20 0.48
PDE4C Q08493 2/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29964428 0.89 GPR119 (0.59) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL69206 0.88 KDM1A (0.56) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL30657430 0.87 KDM1A (0.56) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL26639643 0.87 KDM1A (0.56) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL22265805 0.86 KDM1A (0.55) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL29079766 0.86 KDM1A (0.55) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL3251855 0.84 GPR119 (0.53) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL3250796 0.84 KDM1A (0.53) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL2773558 0.84 GPR119 (0.58) GPR119KDM1APDE4DPDE4BPDE4A
SCHEMBL2764837 0.84 GPR119 (0.55) GPR119KDM1APDE4DPDE4BPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116406360-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2023-07-07 CN disclosed