SCHEMBL29079989

SCHEMBL29079989

O=C1C=C(c2ccc(Br)cc2)CCO1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
HTR2C P28335 2/20 0.36
TSHR P16473 2/20 0.36
WNT3A P56704 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
PTPRC P08575 1/20 0.34
MAPK1 P28482 2/20 0.33
TP53 P04637 2/20 0.33
GAA P10253 2/20 0.33
MAOB P27338 1/20 0.33
PKM P14618 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
PRKDC P78527 1/20 0.33
CYP2A6 P11509 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13492167 0.84 HTR2C (0.36) ALDH1A1HTR2CTSHRWNT3ATNKS2
SCHEMBL29079981 0.80 PTGS1 (0.38) ALDH1A1TSHRWNT3ATNKS2TP53
SCHEMBL29079972 0.80 ALDH1A1 (0.40) ALDH1A1HTR2CTSHRWNT3ATNKS2
SCHEMBL29080010 0.80 PTGS1 (0.40) ALDH1A1TSHRTP53MAOBMEN1
SCHEMBL29079999 0.80 NPC1 (0.43) ALDH1A1MAPK1GAAMEN1MAPT
SCHEMBL980935 0.79 ALDH1A1 (0.41) ALDH1A1TSHRTP53MEN1MAPT
SCHEMBL29080015 0.76 MAPT (0.47) ALDH1A1MAPK1GAAPKMMEN1
SCHEMBL29822666 0.74 NOTUM (0.38) TSHRTP53MAOBMAPTLMNA
SCHEMBL29080019 0.74 NOTUM (0.38) TSHRTP53MAOBMAPTLMNA
SCHEMBL5228519 0.72 HTR2C (0.39) ALDH1A1HTR2CTSHRPTPRCMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853664-B Method for synthesizing alpha, beta-unsaturated cyclohexyl ketone compound under palladium catalysis condition 河南大学 2023-09-29 CN disclosed
CN-114853664-A Method for synthesizing alpha, beta-unsaturated heterocyclic hexyl ketone compound under palladium catalysis condition 河南大学 2022-08-05 CN disclosed