Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535899 | 0.91 | MAPT (0.37) | MAPT | |
| SCHEMBL24535900 | 0.78 | MEN1 (0.39) | MAPT | |
| SCHEMBL30793888 | 0.77 | MAPT (0.37) | MAPT | |
| SCHEMBL25334805 | 0.77 | MEN1 (0.40) | MAPT | |
| SCHEMBL30793812 | 0.75 | F13A1 (0.36) | MAPT | |
| SCHEMBL25335700 | 0.71 | NR1H2 (0.42) | MAPT | |
| SCHEMBL30793679 | 0.68 | RAB9A (0.33) | — | |
| SCHEMBL24535159 | 0.68 | MEN1 (0.36) | MAPT | |
| SCHEMBL30793521 | 0.67 | MEN1 (0.35) | MAPTBACE1 | |
| SCHEMBL30793765 | 0.67 | ADORA1 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829151-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2023-09-29 | — | — | CN | disclosed |