Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319735 | 0.97 | KMT2A (0.32) | KMT2A | |
| SCHEMBL29171522 | 0.93 | KMT2A (0.31) | KMT2A | |
| SCHEMBL29171515 | 0.93 | KMT2A (0.31) | KMT2A | |
| Lithium Ion SCHEMBL30397728 | 0.93 | KMT2A (0.31) | KMT2A | |
| Phosphine SCHEMBL29171517 | 0.90 | KMT2A (0.30) | KMT2A | |
| SCHEMBL29248332 | 0.88 | KMT2A (0.33) | KMT2A | |
| Hydrochloric Acid SCHEMBL28227095 | 0.75 | KMT2A (0.33) | KMT2A | |
| Acrylic Acid SCHEMBL31611194 | 0.72 | KMT2A (0.33) | KMT2A | |
| SCHEMBL21573992 | 0.71 | KMT2A (0.30) | KMT2A | |
| SCHEMBL12562651 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829567-A | Oligonucleotide prodrugs based on cyclic disulfide modified phosphates | 阿尔尼拉姆医药品有限公司 | 2023-09-29 | — | — | CN | disclosed |