Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766405 | 0.89 | CYP19A1 (0.42) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 | |
| SCHEMBL16167547 | 0.82 | TSHR (0.57) | TSHRLMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8956380 | 0.81 | TSHR (0.58) | CYP19A1TSHRALDH1A1POLBMAPT | |
| SCHEMBL7076638 | 0.80 | CYP19A1 (0.48) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 | |
| SCHEMBL11473038 | 0.76 | CYP19A1 (0.43) | CYP19A1TSHRLMNAVCAM1CYP3A4 | |
| SCHEMBL7492090 | 0.74 | CYP19A1 (0.46) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 | |
| SCHEMBL8418034 | 0.74 | TSHR (0.50) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 | |
| SCHEMBL7589332 | 0.74 | TSHR (0.64) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 | |
| SCHEMBL9886148 | 0.74 | CYP19A1 (0.50) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 | |
| SCHEMBL8625816 | 0.73 | CYP19A1 (0.41) | CYP19A1TSHRLMNAVCAM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490705-B | N-macrocyclic amide compound, preparation method thereof and application thereof as medicine | 成都凡诺西生物医药科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-115490705-A | N-macrocyclic amide compound, preparation method thereof and application thereof as medicine | 成都凡诺西生物医药科技有限公司 | 2022-12-20 | — | — | CN | disclosed |