Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14151906 | 0.87 | TSHR (0.55) | TSHRCYP19A1SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL8418034 | 0.86 | TSHR (0.50) | TSHRCYP19A1SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL15542568 | 0.82 | TSHR (0.50) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL716259 | 0.82 | CYP19A1 (0.54) | TSHRCYP19A1SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL78754 | 0.80 | TSHR (0.62) | TSHRSMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL30409299 | 0.80 | TSHR (0.62) | TSHRSMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8609978 | 0.80 | CYP4F2 (0.55) | TSHRSMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL250473 | 0.78 | TSHR (1.00) | TSHRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9886148 | 0.78 | CYP19A1 (0.50) | TSHRCYP19A1SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL11769984 | 0.78 | FFAR1 (0.52) | CYP19A1SMN1; SMN2CYP3A4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117089070-B | Liquid crystal aligning agent and application thereof | 波米科技有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-116789590-B | Diamine compound containing piperidine group, and preparation method and application thereof | 波米科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117089070-A | Liquid crystal aligning agent and application thereof | 波米科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116789590-A | Diamine compound containing piperidine group, and preparation method and application thereof | 波米科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20180008604-A1 | COVALENT INHIBITORS OF CDK-7 | NEWAVE PHARMACEUTICAL LLC | 2018-01-11 | — | — | US | disclosed |
| CN-104673275-A | An activated luminescence material and a method for preparing the same | UNIV HONG KONG SCIENCE & TECHN | 2015-06-03 | — | — | CN | disclosed |
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| CN-1069633-C | Iodo-substituted X-ray contrast agents | NYCOMED IMAGING AS (NO) | 2001-08-15 | — | — | CN | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |
| US-5882628-A | Contrast media | NYCOMED IMAGING AS (NO) | 1999-03-16 | — | — | US | disclosed |
| CN-1166826-A | Iodo-substituted X-ray contrast agents | NYCOMED IMAGING AS (NO) | 1997-12-03 | — | — | CN | disclosed |
| EP-0782564-A1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009282-A1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING A/S (NO) | 1996-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180008604-A1 | COVALENT INHIBITORS OF CDK-7 | CDK7, CDKL1, CDK1 | TSHR 2097/4885CYP19A1 589/4885SMN1; SMN2 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.