Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | TOP1 | P11387 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626290 | 1.00 | KCNH2 (0.57) | KCNH2TOP1KDM4EALDH1A1HPGD | |
| SCHEMBL29080644 | 0.91 | KDM4E (0.58) | TOP1KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL30626277 | 0.91 | KDM4E (0.58) | TOP1KDM4EALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9773874 | 0.90 | TOP1 (0.66) | KCNH2TOP1KMT2ATOP2ATOP2B | |
| SCHEMBL30626285 | 0.88 | ALDH1A1 (0.55) | TOP1KDM4EALDH1A1POLBOPRM1 | |
| SCHEMBL29080640 | 0.88 | ALDH1A1 (0.55) | TOP1KDM4EALDH1A1POLBOPRM1 | |
| Hydrochloric Acid SCHEMBL9773991 | 0.86 | KDM4E (0.68) | KCNH2TOP1KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9774009 | 0.86 | KDM4E (0.68) | KCNH2TOP1KDM4EALDH1A1HPGD | |
| SCHEMBL9773828 | 0.86 | TOP2A (0.57) | KCNH2TOP1KDM4EALDH1A1HPGD | |
| SCHEMBL4366654 | 0.85 | TOP1 (0.54) | KCNH2TOP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606279-A | Fluoroquinolone compound and preparation method and application thereof | 广东工业大学 | 2023-08-18 | — | — | CN | disclosed |