Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151679 | 0.94 | — | — | |
| SCHEMBL28061488 | 0.94 | CLK4 (0.38) | CLK4LRRK2KMOCDK2CTSK | |
| SCHEMBL21670004 | 0.91 | — | — | |
| SCHEMBL30827004 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL7414247 | 0.91 | — | — | |
| Formic Acid SCHEMBL30763006 | 0.79 | RAB9A (0.32) | CLK4KMOALDH1A1GAAKCNMA1 | |
| SCHEMBL24497343 | 0.72 | CLK4 (0.47) | CLK4CDK2ALDH1A1NPSR1NAAA | |
| SCHEMBL1997812 | 0.67 | — | — | |
| SCHEMBL1995715 | 0.67 | — | — | |
| SCHEMBL31754724 | 0.67 | CYP2A6 (0.48) | ALDH1A1MAPTHPGDHSP90AA1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410141-A | Preparation method of avanafil intermediate | 南京艾德凯腾生物医药有限责任公司 | 2023-07-11 | — | — | CN | disclosed |