Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229027 | 0.79 | MEN1 (0.73) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL3716044 | 0.78 | HTT (0.61) | ALDH1A1CYP19A1CA12CA1CA2 | |
| SCHEMBL25171194 | 0.78 | MEN1 (0.70) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL14380626 | 0.78 | MEN1 (0.70) | MEN1KMT2AGAAALDH1A1RECQL | |
| SCHEMBL6338974 | 0.78 | KMT2A (0.70) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL8514619 | 0.72 | MEN1 (0.56) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL4662845 | 0.72 | KEAP1 (0.76) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL2908147 | 0.71 | CA1 (0.57) | MEN1KMT2AGAAALDH1A1CYP19A1 | |
| SCHEMBL26212940 | 0.71 | KDM4E (0.51) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL5960116 | 0.69 | MEN1 (0.73) | MEN1KMT2AL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963337-B1 | THIENO[2,3-b]PYRIDINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2010-09-01 | — | — | EP | disclosed |
| US-20100022521-A1 | COMPOUNDS | HANSA METALLWERKE AG (DE) | 2010-01-28 | — | — | US | disclosed |
| CN-101341152-A | Novel compounds | RICHTER GEDEON NYRT (HU) | 2009-01-07 | — | — | CN | disclosed |
| EP-1963337-A1 | NEW COMPOUNDS | Richter Gedeon NYRT (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072095-A1 | NEW COMPOUNDS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022521-A1 | COMPOUNDS | GRM5, GRM3, GRM1 | MEN1 4389/4885KMT2A 2168/4885GAA 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.