Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32689215 | 1.00 | NPC1 (0.36) | NPC1RAB9AMEN1KMT2AROCK2 | |
| SCHEMBL24367479 | 1.00 | NPC1 (0.36) | NPC1RAB9AMEN1KMT2AROCK2 | |
| SCHEMBL29081492 | 0.92 | NPC1 (0.34) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24366743 | 0.92 | NPC1 (0.34) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29081948 | 0.90 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL32689330 | 0.90 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24364873 | 0.90 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL32689052 | 0.88 | ALDH1A1 (0.35) | NPC1RAB9AKMT2A | |
| SCHEMBL29081781 | 0.88 | ALDH1A1 (0.35) | NPC1RAB9AKMT2A | |
| SCHEMBL25922805 | 0.88 | ALDH1A1 (0.35) | NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |