Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 5/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24514841 | 0.88 | P2RX7 (0.50) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL31570452 | 0.83 | P2RX7 (0.55) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL169762 | 0.72 | P2RX7 (1.00) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL31387242 | 0.72 | P2RX7 (0.59) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL18095998 | 0.71 | P2RX7 (0.48) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL422542 | 0.71 | P2RX7 (0.89) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL31387285 | 0.70 | MAPK1 (0.46) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL14330689 | 0.70 | P2RX7 (0.57) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL17470588 | 0.69 | P2RX7 (0.85) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL16189840 | 0.69 | P2RX7 (0.85) | P2RX7MAPK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615414-A | Substituted 6, 7-dihydro-5H-benzo [7] rotaline compounds and derivatives thereof, method for the production and therapeutic use thereof | 赛诺菲 | 2023-08-18 | — | — | CN | disclosed |