Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27739177 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRL3MBTL1RARB | |
| Bicarbonate SCHEMBL23827507 | 0.82 | FASN (0.39) | TSHRCYP1A2PTPN2PTPN1PTPN11 | |
| Terephthalic Acid SCHEMBL7944128 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRRARBMEN1 | |
| Terephthalic Acid SCHEMBL7944132 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRRARBMEN1 | |
| Benzoic Acid SCHEMBL28839137 | 0.77 | TSHR (0.48) | ALDH1A1TSHRCYP1A2KMT2APTPN2 | |
| SCHEMBL6294879 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRL3MBTL1RARB | |
| SCHEMBL6223194 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRL3MBTL1RARB | |
| SCHEMBL26455401 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRL3MBTL1RARB | |
| SCHEMBL6481935 | 0.76 | — | — | |
| SCHEMBL130706 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116804836-A | Toner containing charge control agent | 施乐公司 | 2023-09-26 | — | — | CN | disclosed |