Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.52 |
| ▸ | MET | P08581 | 4/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.52 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139907 | 0.87 | KDR (0.62) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL142080 | 0.84 | KDR (0.58) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL145838 | 0.81 | KDR (0.54) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL138397 | 0.79 | KDR (0.49) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL141041 | 0.79 | MAPK14 (0.44) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL141722 | 0.79 | MET (0.49) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL142813 | 0.78 | KDR (0.46) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3620026 | 0.78 | MET (0.40) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL141396 | 0.77 | MET (0.43) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL140475 | 0.77 | MET (0.47) | KDRMETNTRK1TEKNTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907339-B | 4- (4-aminophenoxy) pyridin-2-amine derivatives and use thereof | 成都奥睿药业有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114907339-A | 4- (4-aminophenoxy) pyridin-2-amine derivatives and uses thereof | 成都奥睿药业有限公司 | 2022-08-16 | — | — | CN | disclosed |