Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.45 |
| ▸ | KDR | P35968 | 14/20 | 0.44 |
| ▸ | BRAF | P15056 | 10/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083265 | 0.86 | KDR (0.55) | KDRBRAFMET | |
| SCHEMBL2555530 | 0.85 | GCK (0.61) | GCKKDRBRAF | |
| SCHEMBL29788821 | 0.85 | GCK (0.61) | GCKKDRBRAF | |
| SCHEMBL2548367 | 0.85 | GCK (0.44) | GCKKDRBRAF | |
| SCHEMBL2556656 | 0.84 | GCK (0.47) | GCKKDRBRAFMET | |
| SCHEMBL29083258 | 0.84 | KMT2A (0.44) | GCKKDRBRAFMET | |
| SCHEMBL29083253 | 0.83 | CSF1R (0.46) | GCKKDRBRAFMET | |
| SCHEMBL4329896 | 0.81 | P2RX3 (0.49) | GCKKDRBRAF | |
| SCHEMBL29083252 | 0.80 | GCK (0.43) | GCKKDRBRAFMET | |
| SCHEMBL29083254 | 0.80 | GCK (0.44) | GCKKDRBRAFMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907339-B | 4- (4-aminophenoxy) pyridin-2-amine derivatives and use thereof | 成都奥睿药业有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114907339-A | 4- (4-aminophenoxy) pyridin-2-amine derivatives and uses thereof | 成都奥睿药业有限公司 | 2022-08-16 | — | — | CN | disclosed |