SCHEMBL2908330

SCHEMBL2908330

CC1(C)CC(NC(=O)c2ccccc2)CC(C)(C)N1

nearest known ligand 0.89

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 10/20 0.89
KMT2A Q03164 3/20 0.70
MEN1 O00255 2/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
POLB P06746 2/20 0.66
GLA P06280 1/20 0.63
ATM Q13315 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8738588 0.94 EZH2 (1.00) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL169747 0.92 EZH2 (0.80) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL6119822 0.91 EZH2 (0.80) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL310763 0.89 KMT2A (0.82) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL8739251 0.89 EZH2 (0.76) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL8738156 0.89 EZH2 (0.76) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL6120593 0.87 EZH2 (0.74) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL6120964 0.87 EZH2 (1.00) EZH2KMT2AMEN1L3MBTL1GLA
SCHEMBL8739222 0.87 KMT2A (0.70) EZH2KMT2AMEN1L3MBTL1POLB
SCHEMBL8738163 0.87 EZH2 (0.74) EZH2KMT2AMEN1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365380-B1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-04-26 EP disclosed
US-11542389-B2 Vinyl chloride polymers and compositions for additive manufacturing AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-01-03 US disclosed
US-20210017374-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2021-01-21 US disclosed
US-10829629-B2 Vinyl chloride polymers and compositions for additive manufacturing CHEMSON POLYMER-ADDITIVE AG (AT) 2020-11-10 US disclosed
WO-2020058337-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 WO disclosed
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
US-20180305536-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2018-10-25 US disclosed
EP-3365380-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING Chemson Polymer-Additive AG (AT) 2018-08-29 EP disclosed
EP-2436266-B1 Antimicrobial agent for polymers KE KELIT KUNSTSTOFFWERK GES M B H (AT) 2018-04-04 EP disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 EP disclosed
EP-0290391-A2 Polyolefines stabilized against light degradation CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
US-4775386-A Process for photochemical stabilization of undyed and dyed polyamide fibre material and blends thereof with other fibres: copper complex and light stabilizer treatment CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
EP-0255481-A1 Process for the photochemical stabilisation of a fibrous polyamide material and its mixtures with other fibres CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed
EP-0245204-A1 Process for the photochemical stabilization of undyed and dyed fibrous polyamide material and its mixture with other fibres CIBA-GEIGY AG (CH) 1987-11-11 EP disclosed
EP-0237485-A2 Stabilized compositions of rigid PVC CIBA-GEIGY AG (CH) 1987-09-16 EP disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 EP disclosed
US-4396735-A N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-08-02 US disclosed
US-4362831-A A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
US-4202816-A ENOL-PIPERIDINE METAL COMPLEXES CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed
US-4101506-A PIPERIDINE COMPOUNDS, STABILIZERS FOR POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed