1,4-Butanediol

1,4-Butanediol

SCHEMBL29083545

CC(C)COCC(C)C.OCCCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 5/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
MGAM O43451 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3-Propanediol SCHEMBL7196383 0.94 TSHR (0.37) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
Ethylene Glycol SCHEMBL351864 0.88 TSHR (0.41) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL710232 0.87 USP2 (0.42) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
SCHEMBL2527672 0.85 USP2 (0.45) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL2525592 0.85 USP2 (0.45) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL2962278 0.85 HTT (0.41) SMN1; SMN2TSHRLMNAHSD17B10MEN1
SCHEMBL2956370 0.85 HTT (0.41) SMN1; SMN2TSHRLMNAHSD17B10MEN1
SCHEMBL296903 0.83
1,3-Propanediol SCHEMBL7196243 0.83 TSHR (0.39) TSHRALDH1A1L3MBTL1
Alcohol SCHEMBL5571921 0.81 TSHR (0.41) TSHRALDH1A1HSD17B10L3MBTL1MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116670108-A Ether compounds as volatiles for treating amino acid based substrates such as skin and hair 迈图高新材料有限责任公司 2023-08-29 CN disclosed