Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525592 | 0.98 | USP2 (0.45) | USP2SPHK1SPHK2HTTMEN1 | |
| SCHEMBL2527672 | 0.98 | USP2 (0.45) | USP2SPHK1SPHK2HTTMEN1 | |
| SCHEMBL2956370 | 0.98 | HTT (0.41) | USP2SPHK1SPHK2HTTMEN1 | |
| SCHEMBL2962278 | 0.98 | HTT (0.41) | USP2SPHK1SPHK2HTTMEN1 | |
| SCHEMBL296903 | 0.92 | — | — | |
| 1,4-Butanediol SCHEMBL29083545 | 0.87 | SMN1; SMN2 (0.38) | MEN1KMT2ATSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL11858528 | 0.87 | SPHK1 (0.42) | USP2SPHK1SPHK2HTTHSD17B10 | |
| SCHEMBL17530115 | 0.86 | MEN1 (0.56) | USP2SPHK1SPHK2HTTMEN1 | |
| SCHEMBL8810634 | 0.85 | USP2 (0.42) | USP2SPHK1SPHK2HTTMEN1 | |
| Succinic Acid SCHEMBL2961696 | 0.84 | GAA (0.42) | USP2SPHK1SPHK2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| US-7766978-B2 | Acidic hair dyeing method | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2010-08-03 | — | — | US | claimed |
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | claimed |
| EP-2392314-B1 | OILY HAIR COSMETIC | KOKYU ALCOHOL KOGYO CO LTD (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-9617438-B2 | Oily inkjet ink | RISO KAGAKU CORPORATION (JP) | 2017-04-11 | — | — | US | disclosed |
| EP-2237774-B1 | THE USE OF 6-HALOGENO-(1,2,4)-TRIAZOLO-(1,5-a)-PYRIMIDINE COMPOUNDS FOR COMBATING PESTS IN AND ON ANIMALS | MERIAL LTD (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9133209-B2 | Insecticidal 4-amino-thieno[2,3-D]-pyrimidine compounds and methods of their use | MERIAL, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2459569-B1 | INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | MERIAL INC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-9045465-B1 | 3-heterocyclyl-substituted benzoyl derivatives | BASF SE (DE) | 2015-06-02 | — | — | US | disclosed |
| EP-1662877-B1 | 6-HALOGENO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINES FOR COMBATING ANIMAL PESTS | MERIAL LTD (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8664235-B2 | 6-Halogeno-[1,2,4]triazolo[1,5-a]pyrimidines for combating animal pests | MERIAL LIMITED (US) | 2014-03-04 | — | — | US | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4695656-A | Process for the preparation of 2,4-dinitrophenyl ethers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0204111-A2 | Process for the preparation of 2,4-dinitrophenyl ethers | CASSELLA Aktiengesellschaft (DE) | 1986-12-10 | — | — | EP | disclosed |
| EP-0200955-A2 | Process for the preparation of 2,4-dinitrophenyl ethers | CASSELLA Aktiengesellschaft (DE) | 1986-11-12 | — | — | EP | disclosed |
| US-4532239-A | N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0054946-B1 | BASIC SUBSTITUTED PYRIDAZINES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054946-A1 | Basic substituted pyridazines, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4216314-A | CARDIOSELECTIVE B-ADRENOLYTIC AGENTS, ANTIARRHYTHMIC AGENTS AND HYPOTENSIVE AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | H1-0, MRM1, H1-4 | USP2 3520/4885SPHK1 3599/4885SPHK2 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.