Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997009 | 0.90 | TDP1 (0.54) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL11349987 | 0.82 | TDP1 (0.52) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL20607027 | 0.82 | HPGD (0.54) | HPGDNPC1RAB9AKDM4ELMNA | |
| SCHEMBL29083864 | 0.81 | ESR1 (0.46) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL29083828 | 0.81 | KMT2A (0.49) | KDM4ELMNAALDH1A1MAPTKMT2A | |
| SCHEMBL11358502 | 0.81 | GAA (0.63) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL9678892 | 0.81 | ALDH1A1 (0.70) | HPGDNPC1RAB9AKDM4ELMNA | |
| SCHEMBL22838188 | 0.81 | TDP1 (0.53) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL25550796 | 0.81 | ALDH1A1 (0.70) | HPGDNPC1RAB9AKDM4ELMNA | |
| SCHEMBL28152538 | 0.81 | HPGD (0.53) | HPGDNPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813584-A | Preparation method of dronedarone hydrochloride intermediate | 山东新时代药业有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116410211-A | Benzofuran compound | 山东新时代药业有限公司 | 2023-07-11 | — | — | CN | disclosed |