Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 13/20 | 0.51 |
| ▸ | WEE1 | P30291 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084074 | 0.91 | ALK (0.51) | PDGFRBPDGFRAEGFRWEE1FGFR1 | |
| SCHEMBL29083991 | 0.90 | ALK (0.50) | PDGFRBPDGFRAEGFRWEE1FGFR1 | |
| SCHEMBL29084068 | 0.90 | EGFR (0.55) | PDGFRBPDGFRAEGFRWEE1FGFR1 | |
| SCHEMBL29083947 | 0.89 | ALK (0.62) | PDGFRBPDGFRAEGFRWEE1FGFR1 | |
| SCHEMBL29084119 | 0.88 | EGFR (0.55) | EGFRFGFR1 | |
| SCHEMBL29083999 | 0.88 | EGFR (0.53) | EGFRWEE1FGFR1 | |
| SCHEMBL29083958 | 0.86 | EGFR (0.52) | EGFRFGFR1 | |
| SCHEMBL29084076 | 0.86 | EGFR (0.53) | PDGFRBPDGFRAEGFRINSRIGF1R | |
| SCHEMBL29084093 | 0.85 | EGFR (0.48) | PDGFRBPDGFRAEGFRPLK1INSR | |
| SCHEMBL29084102 | 0.84 | EGFR (0.55) | EGFRPLK1INSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | claimed |
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | disclosed |