Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.55 |
| ▸ | INSR | P06213 | 4/20 | 0.52 |
| ▸ | IGF1R | P08069 | 4/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084091 | 0.95 | EGFR (0.53) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29084008 | 0.94 | INSR (0.52) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29083973 | 0.94 | EGFR (0.62) | EGFRINSRIGF1RALK | |
| SCHEMBL29084099 | 0.94 | EGFR (0.53) | EGFRINSRIGF1RALK | |
| SCHEMBL29084016 | 0.92 | EGFR (0.57) | EGFRINSRIGF1RALK | |
| SCHEMBL29084119 | 0.92 | EGFR (0.55) | EGFR | |
| SCHEMBL29084058 | 0.91 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL29974268 | 0.91 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL29083947 | 0.90 | ALK (0.62) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29084051 | 0.90 | EGFR (0.56) | EGFRINSRIGF1RALKPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | claimed |
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | disclosed |