Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13252835 | 0.96 | MAPT (0.58) | MAPTRAB9APSMD10TDP1L3MBTL1 | |
| SCHEMBL30325035 | 0.96 | MAPT (0.58) | MAPTRAB9APSMD10TDP1L3MBTL1 | |
| SCHEMBL30325226 | 0.96 | MAPT (0.58) | MAPTRAB9APSMD10TDP1L3MBTL1 | |
| SCHEMBL29768658 | 0.94 | PSMD10 (0.59) | MAPTRAB9APSMD10TDP1L3MBTL1 | |
| SCHEMBL29768597 | 0.92 | PSMD10 (0.58) | MAPTRAB9APSMD10TDP1L3MBTL1 | |
| SCHEMBL11111198 | 0.86 | STAT3 (0.59) | L3MBTL1CA12CA1CA9ALDH1A1 | |
| SCHEMBL8069545 | 0.86 | CA12 (0.63) | L3MBTL1CA12CA1CA9LMNA | |
| SCHEMBL13873578 | 0.85 | GAA (0.54) | MAPTTDP1L3MBTL1CA12CA1 | |
| SCHEMBL13252830 | 0.85 | CA12 (0.47) | MAPTRAB9APSMD10TDP1L3MBTL1 | |
| SCHEMBL29084505 | 0.85 | TCF4 (0.53) | MAPTRAB9APSMD10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438177-A | Targeted chimeric compounds, pharmaceutical compositions containing same, and preparation methods and uses thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022161166-A1 | TARGETING CHIMERIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-08-04 | — | — | WO | disclosed |