Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115493 | 1.00 | USP30 (0.62) | USP30L3MBTL1MAPTHDAC4NAMPT | |
| SCHEMBL29085260 | 1.00 | USP30 (0.62) | USP30L3MBTL1MAPTHDAC4NAMPT | |
| SCHEMBL30065244 | 0.86 | USP30 (0.55) | USP30MAPTNAMPTMEN1KMT2A | |
| SCHEMBL29085165 | 0.81 | CCNA2 (0.45) | USP30MAPTHDAC4MEN1KMT2A | |
| SCHEMBL29085252 | 0.81 | CCNA2 (0.45) | USP30MAPTHDAC4MEN1KMT2A | |
| SCHEMBL30604687 | 0.81 | CCNA2 (0.45) | USP30MAPTHDAC4MEN1KMT2A | |
| SCHEMBL29085200 | 0.81 | USP30 (0.56) | USP30MAPTNAMPTNPC1ALDH1A1 | |
| SCHEMBL29085175 | 0.81 | USP30 (0.56) | USP30MAPTNAMPTNPC1ALDH1A1 | |
| SCHEMBL29960478 | 0.81 | USP30 (0.56) | USP30MAPTNAMPTNPC1ALDH1A1 | |
| SCHEMBL29085179 | 0.81 | USP30 (0.56) | USP30MAPTNAMPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116710433-A | Selective PARP1 inhibitor and application thereof | 成都百裕制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022222964-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |
| WO-2022222966-A1 | SELECTIVE PARP1 INHIBITOR AND APPLICATION THEREOF | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |