Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.55 |
| ▸ | NAMPT | P43490 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085167 | 0.86 | USP30 (0.62) | USP30NAMPTHPGDNPC1ALOX15 | |
| SCHEMBL29115493 | 0.86 | USP30 (0.62) | USP30NAMPTHPGDNPC1ALOX15 | |
| SCHEMBL29085260 | 0.86 | USP30 (0.62) | USP30NAMPTHPGDNPC1ALOX15 | |
| SCHEMBL29960478 | 0.86 | USP30 (0.56) | USP30NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29085175 | 0.86 | USP30 (0.56) | USP30NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29085200 | 0.86 | USP30 (0.56) | USP30NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29085179 | 0.86 | USP30 (0.56) | USP30NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29085171 | 0.84 | USP30 (0.48) | USP30NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29115445 | 0.76 | NAMPT (0.52) | USP30NAMPTNPC1RAB9ABRAF | |
| SCHEMBL29115443 | 0.76 | NAMPT (0.52) | USP30NAMPTNPC1RAB9ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222964-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |