Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385542 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29020772 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30385497 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30385538 | 0.84 | MAPT (0.60) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL25738505 | 0.84 | MAPT (0.60) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085250 | 0.84 | BACE1 (0.46) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30604692 | 0.84 | MAPT (0.54) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085218 | 0.84 | MAPT (0.54) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30604698 | 0.84 | MAPT (0.54) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085192 | 0.84 | MAPT (0.54) | SMN1; SMN2MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2022222964-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |