Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202813 | 0.88 | BACE1 (0.47) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29085235 | 0.87 | BACE1 (0.46) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29085176 | 0.84 | SMN1; SMN2 (0.55) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL25234852 | 0.83 | BACE1 (0.48) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL31042189 | 0.83 | BACE1 (0.48) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29085165 | 0.83 | CCNA2 (0.45) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30604687 | 0.83 | CCNA2 (0.45) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29085252 | 0.83 | CCNA2 (0.45) | BACE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29085237 | 0.82 | TYK2 (0.39) | BACE1MAPTSCN9AALDH1A1TYK2 | |
| SCHEMBL22912731 | 0.81 | BACE1 (0.52) | BACE1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2022222964-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |