Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085243 | 1.00 | CNR2 (0.42) | CNR2SCN9APARP1CSNK1ECHRM4 | |
| SCHEMBL29085245 | 0.86 | BACE1 (0.45) | CNR2SCN9AKMT2A | |
| SCHEMBL29085207 | 0.86 | SCN9A (0.43) | CNR2SCN9APARP1CHRM4SCN7A | |
| SCHEMBL29085203 | 0.86 | SCN9A (0.43) | CNR2SCN9APARP1CHRM4SCN7A | |
| SCHEMBL29085247 | 0.84 | CNR2 (0.37) | CNR2SCN9APARP1CHRM4SCN7A | |
| SCHEMBL30065244 | 0.76 | USP30 (0.55) | NAMPTKMT2A | |
| SCHEMBL30604687 | 0.75 | CCNA2 (0.45) | CNR2SCN9AKMT2A | |
| SCHEMBL29085228 | 0.75 | GPR6 (0.46) | PARP1 | |
| SCHEMBL30064980 | 0.74 | PARP1 (0.54) | PARP1PRKAA2 | |
| SCHEMBL29085174 | 0.74 | SCN9A (0.43) | CNR2SCN9APARP1CHRM4SCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |