Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | PYGB | P11216 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647982 | 0.67 | EPHX1 (0.41) | ALDH1A1EPHX1 | |
| SCHEMBL4680638 | 0.65 | MAPT (0.40) | ALDH1A1MAPTNPSR1EPHX1 | |
| SCHEMBL4016350 | 0.64 | EPHX1 (0.39) | ALDH1A1EPHX1 | |
| SCHEMBL9062785 | 0.64 | — | — | |
| SCHEMBL16119131 | 0.64 | — | — | |
| SCHEMBL10538036 | 0.62 | MAPT (0.57) | ALOX15ALDH1A1MAPTNFKB1NFKB2 | |
| SCHEMBL5888258 | 0.61 | — | — | |
| SCHEMBL2050427 | 0.60 | — | — | |
| SCHEMBL8464579 | 0.60 | EPHX1 (0.46) | ALDH1A1MAPTNPSR1EPHX1 | |
| SCHEMBL23636521 | 0.60 | MAPT (0.42) | ALDH1A1MAPTNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1657243-B1 | Procedure for the production of amino alcohols | LONZA AG (CH) | 2010-08-18 | — | — | EP | disclosed |