SCHEMBL29087941

SCHEMBL29087941

Cc1ccccc1C(=O)OC1CCN(C(=O)O)C(C)C1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 5/20 0.46
SCN2A Q99250 5/20 0.46
SCN3A Q9NY46 5/20 0.46
ATM Q13315 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
CHRNA7 P36544 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
PIK3CD O00329 1/20 0.38
CYP1A2 P05177 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29087925 0.85 MEN1 (0.42) SCN1ASCN2ASCN3AATMMEN1
SCHEMBL27929943 0.76 SCN1A (0.50) SCN1ASCN2ASCN3AATMMEN1
SCHEMBL19765487 0.75 MEN1 (0.58) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL8550391 0.73 POLB (0.62) SCN1ASCN2ASCN3AALDH1A1
SCHEMBL30410538 0.73 ATM (0.53) SCN1ASCN2ASCN3AATMMEN1
Hydrochloric Acid SCHEMBL8556314 0.72 POLB (0.61) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL6057170 0.72 NPC1 (0.54) SCN1ASCN2ASCN3AATMMEN1
SCHEMBL744096 0.70 CHRNA7 (0.54) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL29087917 0.70 GPR119 (0.52) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL28316315 0.70 MAPT (0.48) SCN1ASCN2ASCN3AATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655599-A Synthesis and application of EGFR allosteric inhibitors 江南大学 2023-08-29 CN disclosed