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SCHEMBL2908808

SCHEMBL2908808

Cc1ccccc1NC(=O)c1cc(C(=O)Nc2ccccc2C)cc(C(=O)Nc2ccccc2C)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 3/20 0.79
▸ POLB P06746 3/20 0.79
▸ NPC1 O15118 3/20 0.70
▸ RAB9A P51151 3/20 0.70
▸ TAS1R3 Q7RTX0 1/20 0.67
▸ TAS1R1 Q7RTX1 1/20 0.67
▸ TAS1R2 Q8TE23 1/20 0.67
▸ ALDH1A1 P00352 5/20 0.62
▸ MEN1 O00255 3/20 0.62
▸ KMT2A Q03164 3/20 0.62
▸ GAA P10253 1/20 0.62
▸ HTT P42858 2/20 0.61
▸ LMNA P02545 2/20 0.61
▸ KDM4E B2RXH2 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ HSD17B10 Q99714 1/20 0.61
▸ KDM4C Q9H3R0 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ TP53 P04637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9055150 0.90 HPGD (0.89) HPGDPOLBNPC1RAB9ATAS1R3
N-O-Tolylbenzamide SCHEMBL3223289 0.88 HPGD (1.00) HPGDPOLBNPC1RAB9AALDH1A1
SCHEMBL6864568 0.88 HPGD (0.67) HPGDPOLBNPC1RAB9ATAS1R3
SCHEMBL21870358 0.88 POLB (0.67) HPGDPOLBNPC1RAB9ATAS1R3
SCHEMBL15556976 0.88 TOP1 (0.77) HPGDPOLBNPC1RAB9ATAS1R3
SCHEMBL12847635 0.85 MEN1 (0.77) HPGDPOLBNPC1RAB9ATAS1R3
SCHEMBL2908895 0.85 MAPT (0.62) HPGDPOLBNPC1RAB9AALDH1A1
SCHEMBL3690383 0.85 POLB (0.79) HPGDPOLBNPC1RAB9AALDH1A1
SCHEMBL18773840 0.84 KMT2A (0.84) HPGDPOLBNPC1RAB9AALDH1A1
SCHEMBL2732354 0.83 HPGD (0.77) HPGDPOLBNPC1RAB9ATAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 — — US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 — — US disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 — — US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 — — US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 — — US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 — — US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 — — US disclosed
EP-2026965-B1 MONO- AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2010-09-01 — — EP disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 — — US disclosed
US-7479515-B2 Polypropylene resin compositions CIBA SPECIALTY CHEMICALS CORP. (US) 2009-01-20 — — US disclosed
US-20070170398-A1 Polypropylene resin compositions SCHMIDT HANS-WERNER 2007-07-26 — — US disclosed
US-7235191-B2 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 — — US disclosed
US-20040063830-A1 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORPORATION 2004-04-01 — — US disclosed