SCHEMBL2908895

SCHEMBL2908895

Cc1cccc(NC(=O)c2cc(C(=O)Nc3cccc(C)c3C)cc(C(=O)Nc3cccc(C)c3C)c2)c1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.62
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
LMNA P02545 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.61
TP53 P04637 3/20 0.61
HTT P42858 2/20 0.61
HSD17B10 Q99714 2/20 0.61
TSHR P16473 1/20 0.61
ATM Q13315 1/20 0.59
HPGD P15428 2/20 0.58
POLB P06746 1/20 0.58
RXFP1 Q9HBX9 2/20 0.57
ALDH1A1 P00352 1/20 0.56
PKM P14618 1/20 0.54
NFKB1 P19838 1/20 0.54
RECQL P46063 1/20 0.54
NFKB2 Q00653 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11769542 0.87 POLB (0.77) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL30288146 0.87 POLB (0.77) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL2908808 0.85 HPGD (0.79) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL20511115 0.84 MAPT (0.65) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL7996943 0.84 SMN1; SMN2 (0.60) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL27678416 0.83 RAB9A (0.61) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL96026 0.83 MAPT (0.63) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL7295331 0.82 RAB9A (0.67) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL13536587 0.82 MAPT (0.62) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL2560246 0.81 MAPT (0.55) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 US disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed
EP-2026965-B1 MONO- AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2010-09-01 EP disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 US disclosed
US-7479515-B2 Polypropylene resin compositions CIBA SPECIALTY CHEMICALS CORP. (US) 2009-01-20 US disclosed
US-20070170398-A1 Polypropylene resin compositions SCHMIDT HANS-WERNER 2007-07-26 US disclosed
US-7235191-B2 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
EP-1366116-B1 POLYPROPYLENE RESIN COMPOSITIONS CIBA SC HOLDING AG (CH) 2006-07-19 EP disclosed
US-20040063830-A1 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORPORATION 2004-04-01 US disclosed