Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731483 | 0.89 | TP53 (0.68) | ESR1LMNATP53TSHRPLA2G4B | |
| SCHEMBL15101927 | 0.84 | LTA4H (0.63) | ESR1CYP3A4NR1I2NR3C1PGR | |
| SCHEMBL5820211 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL382171 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL5819932 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL5814527 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL382628 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL4798961 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL4801986 | 0.82 | TP53 (0.68) | LMNATP53TSHRPLA2G4BLTA4H | |
| SCHEMBL19859208 | 0.82 | TP53 (0.59) | ESR1TP53TSHRPLA2G4BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903691-A | Fluorescent nucleic acid material with humidity indication function and preparation method thereof | 青岛科技大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116903691-A | Fluorescent nucleic acid material with humidity indication function and preparation method thereof | 青岛科技大学 | 2023-10-20 | — | — | CN | disclosed |