Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 19/20 | 0.37 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26917595 | 0.84 | CBLB (0.38) | CBLB | |
| SCHEMBL26917486 | 0.81 | CBLB (0.42) | CBLB | |
| SCHEMBL29089865 | 0.77 | CBLB (0.38) | CBLB | |
| SCHEMBL26917210 | 0.77 | CBLB (0.35) | CBLB | |
| SCHEMBL29575165 | 0.76 | CBLB (0.48) | CBLB | |
| SCHEMBL22528114 | 0.76 | CBLB (0.48) | CBLB | |
| SCHEMBL29089770 | 0.76 | CBLB (0.42) | CBLBCBLC | |
| SCHEMBL29089884 | 0.73 | HSD11B1 (0.39) | CBLB | |
| SCHEMBL25413727 | 0.73 | CBLB (0.42) | CBLB | |
| SCHEMBL22527918 | 0.72 | CBLB (0.48) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288429-A1 | LACTAMS AS CBL-B INHIBITORS | Genentech, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116888112-A | Lactams as CBL-B inhibitors | 基因泰克公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022169997-A1 | LACTAMS AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2022-08-11 | — | — | WO | disclosed |